Associations between KCNJ6 (GIRK2) gene polymorphisms and pain-related phenotypes
نویسندگان
چکیده
منابع مشابه
Association between KCNJ6 (GIRK2) Gene Polymorphisms and Postoperative Analgesic Requirements after Major Abdominal Surgery
Opioids are commonly used as effective analgesics for the treatment of acute and chronic pain. However, considerable individual differences have been widely observed in sensitivity to opioid analgesics. We focused on a G-protein-activated inwardly rectifying potassium (GIRK) channel subunit, GIRK2, that is an important molecule in opioid transmission. In our initial polymorphism search, a total...
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ژورنال
عنوان ژورنال: Pain
سال: 2013
ISSN: 0304-3959
DOI: 10.1016/j.pain.2013.08.026